THE BACILLUS LEPRÆ: HAS IT BEEN CULTIVATED ?

The Biochemistry of Bacillus Lepræ

Since the cultivation, about two years ago, of the leprosy bacillus, increased attention has been directed to the study of immunity processes in infection caused by this microSrganism. Experiments which aim at the development of some method for the specific treatment of the disease have already been undertaken by Dr. Duval and his associates in this laboratory, and by Clegg in the Philippines. ...

The Cultivation of the Bacillus Lepræ

Bacillus Lepræ, Gnats and Bugs

Dear Sir,?You will be glad to learn that Dr. W. J. Goodhue, Medical Superintendent of the Leper Settlement at Molokai, after several years of investigation there, has been able to demonstrate the bacillus lepra? of Hansen in the mosquito and in the bed-bug. I will quote, from Dr. Goodliue'3 official (but as yet private) report to the Hawaian Board of Health : February 10th, 1906. " We have sinc...

Chlorthalidone: has it always been the best thiazide-type diuretic?

Modern diuretic therapy evolved from 2 seemingly unrelated events in the 1930s: the development of sulfanilamide, the first truly effective antibacterial agent, and the description of the enzyme carbonic anhydrase. Sulfanilamide was observed to increase sodium (Na )/potassium and water excretion by inhibition of carbonic anhydrase activity. Recognition of this action proved the impetus for synt...

MPI in 2002: Has it Been Ten Years Already?

In April of 1992, a group of parallel computing vendors, computer science researchers, and application scientists met at a one-day workshop and agreed to cooperate on the development of a community standard for the message-passing model of parallel computing. The MPI Forum that eventually emerged from that workshop became a model of how a broad community could work together to improve an import...